Slavia made light work of their MOL Cup Round of 16 clash away at Zlín, securing a dominant 4–0 victory. The Reds decided the game already in the first half, when Mojmír Chytil opened the scoring. After the break, Lukáš Provod and youngster Tomáš Jelínek — who netted his first-ever senior goal — added insurance strikes, before Michal Sadílek sealed the win late on.

In the third round of the Champions League group stage, Slavia Prague held Atalanta to a 0–0 draw in Bergamo. The hero of the match was Jakub Markovič, who made at least four phenomenal saves on his Champions League debut. The “Red-and-Whites” picked up their second point in the group standings.

In the second round of the Champions League group stage, Slavia Prague were defeated 0–3 away to Inter Milan at the San Siro. Jindřich Staněk was beaten twice by Lautaro Martínez, a veteran of the sides’ memorable 1–1 draw six years ago, while Denzel Dumfries added a third for the hosts.